Coronavirus
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- utopian1
'Swept Up by FEMA': Complicated Medical Supply System Sows Confusion
In Massachusetts, state leaders said they had confirmed a vast order of personal protective equipment for their health workers; then the Trump administration took control of the shipments.
https://www.yahoo.com/news/swept…
#MAGA Proud
- qoob-2
- Anyone know where to buy it?qoob
- trumpcure.commonospaced
- Be sure to take double the recommend dose to really kick the corona's ass....shapesalad
- Actually don't do that, you'll very likely kill yourself... dosage can go from ok to very very not ok with the slightest increase in dose size.shapesalad
- With Zinc https://twitter.com/…BustySaintClaire
- lol@mononeverscared
- please, if you support trump, take triple dose and mix it in with the gallon of kunt-aid you drink each morningmonospaced
- Harsh but posibly fair.webazoot
- even bobo pointed out its $2.50 a bottle so you know these gullible assholes are ready to prove their blind trust in a clown for critical medical advice.monospaced
- shapesalad1
http://theconversation.com/a-sma…
On Saturday the Food and Drug Administration approved the use of two antimalarial drugs, hydroxychloroquine and a related medication, chloroquine, for emergency use to treat COVID-19. The drugs were touted by President Trump as a “game changer” for COVID-19.
However, a study just published in a French medical journal provides new evidence that hydroxychloroquine does not appear to help the immune system clear the coronavirus from the body. The study comes on the heels of two others - one in France and one in China - that reported some benefits in the combination of hydroxychloroquine and azithromycin for COVID-19 patients who didn’t have severe symptoms of the virus.
I am a medicinal chemist who has specialized in discovery and development of antiviral drugs for the past 30 years, and I have been actively working on coronaviruses for the past seven. I am among a number of researchers who are concerned that this drug has been given too much of a high priority before there is enough evidence to show it is indeed effective.
There are already other clinical studies that showed it is not effective against COVID-19 as well as several other viruses. And, more importantly, it can have dangerous side effects, as well as giving people false hope. The latter has led to widespread shortages of hydroxychloroquine for patients who need it to treat malaria, lupus and rheumatoid arthritis, the indications for which it was originally approved.
The idea that the combination of hydroxychloroquine with an antibiotic drug, azithromycin, was effective against COVID-19 gained more attention after a study published on March 17. This study described a trial of 80 patients carried out by Philippe Gautret in Marseille, France. Although some of their results appeared to be encouraging, it should also be noted that most of their patients only had mild symptoms. Furthermore, 85% of the patients didn’t even have a fever – one of the major telltale symptoms of the virus, thus suggesting that these patients likely would have naturally cleared the virus without any intervention.
In another study, posted on medRxiv, which has not yet been peer-reviewed, Chinese scientists from Renmin Hospital of Wuhan University, in Wuhan, China, gave hydroxychloroquine to patients with only mild infections who were free of medical issues, similar to the Gautret study. The results showed that the 31 patients who received the drug showed a lessening of their symptoms 24 hours earlier than patients in the control group. In addition, pneumonia symptoms improved in 25 of the 31 patients versus 17 of 31 in the control group. As noted in several of the comments associated with the manuscript, there are issues related to the translation of the paper, thus clouding interpretations of some of the results. The paper also appears to focus more on pneumonia than COVID-19. However, these issues may be cleared up or addressed once the paper finishes the peer-review process.
But two other studies have conflicting results.
A second French group, led by Jean-Michel Molina, has now tested the hydroxychloroquine-azithromycin combination treatment in 11 patients at the Hôpital Saint-Louis in Paris, France, and their results were strikingly different.
Like the Marseille study, the Molina trial was also a small pilot study. Molina and colleagues used the same dosing regimen as Gautret. In contrast, however, to the Gautret study, eight of the 11 patients had underlying health conditions, and 10 of 11 had fevers and were quite ill at the time the dosing began.
These Paris researchers found that after five to six days of treatment with hydroxychloroquine (600 mg per day for 10 days) and azithromycin (500 mg on day 1 and 250 mg on days 2 to 5), eight of the 10 patients still tested positive for COVID-19. Of these 10 patients, one patient died, two were transferred to the ICU and another had to be removed from the treatment due to serious complications.
In addition, a similar study in China also showed no difference in viral clearance after seven days either with or without the hydroxychloroquine with the patients in the trial. This supports Molina’s findings.
Thus, despite the recent approval of this drug for use against COVID-19, questions remain as to the efficacy of this treatment. As Molina and colleagues note: “Ongoing randomized clinical trials with hydroxychloroquine should provide a definitive answer regarding the alleged efficacy of this combination and will assess its safety.”
- Theres a good breakdown of the French study here https://www.theguard…webazoot
- if approved doesn't mean it's actually used, just that doctors can consider itgrafician
- i.e. a good breakdown of how bad a study it was.webazoot
- Ramanisky20
- Good for her.PhanLo
- "data is anecdotal" hahaha.dorf
- Or she recovered by all other treatments like most people.monospaced
- allthethings1
Ladies and gentlemen, the Wisconsin speaker of the house (R-Hell).
- Bennn0
'' Chinese telecommunications giant Huawei is quietly flying millions of masks to Canada
.. Huawei’s gifts come as the company seeks a key federal approval to install its 5G technology on Canadian mobile networks ''
https://www.theglobeandmail.com/…
See all the posts i've made in the China thread.... China’s Grand Plan To Take Over The World... Almost there, almost there.
- The irony that xenophobic rednecks flock for their insatiable desire for cheap cheap cheap china made products at Walmart.inteliboy
- Huawei Apple clones included.inteliboy
- Canada loves pulling this kind of shitnb
- In Feb, when the Chinese were lying, saying it was contained, we sent 16 tonnes of equipment to them. They returned that favour be sending us Chinese plague.BustySaintClaire
- oh bobomonospaced
- 60,000 masks Toronto got from China had to be recalled after distribution because they were defectiveGnash
- Isn’t it to free the Huawei princess that we’re holding captive?_niko
- Also, _niko. China is always playing strategically with their ultimate Goal in sight.Bennn
- Ramanisky23
https://slate.com/news-and-polit…
Milwaukee residents waited between 90 minutes and 2½ hours to vote on Tuesday, after a coronavirus-induced poll worker shortage forced the city to reduce 180 polling places to just five and a last-ditch effort by the state’s governor to postpone the election was overturned by the state Supreme Court.
- bliznutty0
- lol okaymonospaced
- I think I'll follow mg33 into an info blackout.
Posts like this have just way too much stupid in them for any one person to adequately cope with.Continuity - RFK Jr is an anti vax nutcase.BusterBoy
- my guess is you're a vax nutcasebliznutty
- Akagiyama4
Wow....just, wow.
- Keepin' it surreal son!PhanLo
- Everyone in the world is wrong about COVID-19, except for Trump and his tippy top administration.utopian
- You think you're upset, Bill Gates' pandemic dream scenario just got squashed by President Trump's vocal efficacy of HCQ.robotron3k
- He's talking about himselflowimpakt
- this cretin has to god_gitale
- One thing about WHO he is right, they have beeing promoting unproved traditional Chinese "medicine".dmay
- cheerleader trump blames his unborn baby why he had to fuck a porn star.neverscared
- 'China' 'and we fund it' The catch phrases of the decade.shapesalad
- Dystopian nightmare.ideaist
- "Very powerful hold".
Fuck I want to punch him.BusterBoy - Maybe the best projectionist ever!!Green_Pork
- lowimpakt1
Trump is blaming the WHO, and anyone else imaginable, because yesterday all media including Fox, CNN, New York Times etc reported on the fact that Peter Novarro, Trump's top trade advisor, provided the president with a memo in January with a stark warning of the scale of the problem.
- grafician0
a company/startup seems to have fixed the scale problem of testing:
https://www.billiontoone.com/cov…
"BillionToOne developed a novel qSanger-COVID-19 Test that is more than 30x higher throughput than existing quantitative PCR (qPCR) methods and is highly accurate and cost-effective.
Combining the unused Sanger sequencer capacity from the Human Genome project and the proprietary machine learning algorithm, BillionToOne’s qSanger-COVID-19 unlocks millions of daily testing capacity worldwide.
Test reagents will be made available in 2 weeks to clinical laboratories, pending manufacturing of kits and Emergency Use Authorization from FDA."
We’re unlocking 1+ million COVID-19 testing capacity per day in the US alone
using a unique testing protocol with 30X+ higher throughput- CTO explains a few things here:
https://news.ycombin…sted - ^yeah was about to post that too, thanks for reaching firstgrafician
- CTO explains a few things here:
- i_was0
Fat people more incline to contract Covid19
- more surface to get infected or what‘s your argument?uan
- @uan LOLFixMiller
- Because of the conditions obesity comes with: diabetes and heart diseasemonospaced
- Their inherent increase in gravity causes the virus to enter into an orbit around them. And since the obese travel in herds, the virus spreads more quicklyGnash
- and obviously it‘s harder to outrun the virus with more weight.uan
- Fat people are more inclined to get a lot of shit.Continuity
- Dammit, I'm screwed!Akagiyama
- LOL @GnashKrassy
- @uan It's a fact, statistics are arisingi_was
- sorry. it was stupid sarcasm because we learned about what mono explained two weeks ago around here.uan
- drgs0
* Huge drop-off in air pollution
* Animals reclaim the wilderness
* Kills all unproductive, senescent and weak
* Motivates the rest to get slimmerWe should do it every year, right after Ramadan
- it came out a bit to strong though...we‘ll need some sort of orgies season to balance it out.uan
- *Makes us horny as hellNBQ00
- Hey, that's a good solution, the orgy thing.Continuity
- Ramanisky22
- They're out to save your soul not your body.deadsperm
- Cult on TV for the masses. This is pure madness.Bennn
- Have to respect the hustle. Don't hate the player.deadsperm
- Taxes paid: $0
Souls saved: 0monospaced - Luke 18:13deadsperm
- Haha Joyce, you loserGnash
- LOL. I guess women do get paid less. But then they also say that a woman's work is never done.deadsperm
- Exploiting stupidityBennn
- 'Credulous Dollar'? WTF is this, televangelism, or professional 'wrestling'?Continuity
- Osteen is only worth 40 mil? I thought it'd be a lot more.Akagiyama
- Lol these guys and pro wrestlers are the exact same shit, fake, over the top, great on the mic and a devout following of rednecks_niko
- Kenneth is leading and richest guy? Damn, my boy is doing well.NBQ00
- @continuity That's actually a typo. His actual name is "Creflo Dollar". You can find his mugshot from the time he punched and choked out his 15yo daughter.garbage
- Punches For threadKrassy
- But somebody hand this list to Covid-19 and tell it to get to work.garbage
- ^ lolRamanisky2
- Fake newsinstrmntl
- Nairn0
"A (possible) solution to COVID-19"
https://www.tillett.info/2020/04…- one big issue i can find with this is that the virus has been found to have mutated back on itself in loops. a (theoretically dubious) asymptomatic strain couldkingsteven
- mutate back in to one that kills you.kingsteven
- Is that right? I heard that immunity is almost guaranteed. Maybe I’m not clear.monospaced
- i don't mean in one individual mono. ie. someone gets the asymptomatic strain as vaccine, mutates inside them and infects others with a more harmful versionkingsteven
- Woudln't that be an equivalent risk with attenuated strains like Smallpox or polio, etc, which were used to essentially erradicate them?Nairn
- There isn’t a separate unsymptomatic strain though.monospaced
- My understanding is that it’s still just one virus not multiple versions.monospaced
- The research he refers to from Iceland suggests there might be - at least, it would be worth the search.Nairn
- The differences in symptoms come down to a he host body itself (the person).monospaced
- Not surprised if it mutates. Not at all. It will.monospaced
- @Nairn, i read that the speed of mutation is down to the size of the genome, this is why we cant vaccinate for all flu viruses (they have a shorter genome sokingsteven
- mutate much quicker) i have no idea about polio and pox viruses... I guess theres always a risk... https://is.gd/SxxjyH…kingsteven
- @mono - it's 'one' virus, but under an umbrella of ever-evolving multiple mutations: https://nextstrain.o…Nairn
- Whoahmonospaced
- there was a research paper early in the sequencing of the virus that suggested two strains of SARS-CoV2 and many about misinterpretations of datakingsteven
- it'll be interesting when this is all over to read about what was important and what was noisekingsteven
- Interesting idea, but the virus is the same, it manifests itself more or less harmful depending on the victim's immune system and body/biology, so no luckgrafician
- it mutates ever time it iterates itself:
https://theconversat…shapesalad - learn some basics on life/gentics/dna etc:shapesalad
- https://www.youtube.…shapesalad
- You've got to be fucking kidding me, shape. You think a link to a elementary video makes your case? REALLY?monospaced
- heard on the news that there was a case reported of China of someone becoming infected twice. I can't remember if they died the second time around.instrmntl
- monospaced0
“There’s a rumor out there that because it takes care of lupus very effectively, as I understand it, and it’s a, you know, a drug that’s used for lupus,” he said, “so there’s a study out there that says people that have lupus haven’t been catching this virus. Maybe it’s true; maybe it’s not.” — President Trump
There is no such study.
- "Maybe it’s true; maybe it’s not."Nairn
- I always say that when I cite a fictional study and I’m addressing the nation during a global pandemic.monospaced
- I suspect Trump has that line go through his head after pretty much everything he says publicly.Nairn
- What’s so interesting is that being a president hasn’t changed this guy’s behavior at at all. He’s the same mook he’s always been.Gnash
- I mean, any one of us would perk up a bit if we were at a the house of a friend’s parent. The guy can’t even do when addressing the nation.Gnash
- What trump mook is downvoting?monospaced
- ye don't get the downvoting, "There is no such study", loli_was
- Nairn13
Twitter's Jack Dorsey donates 28% of his wealth - $1Bn - to fight Covid-19.
- Vapour-rich guy donates some of his vapourGnash
- Given that vapour can condense into actual money, it's a bit rich to cheapen his efforts.
See what I did there?Nairn - Admirable, considering most his wealth is probably twitter stock, which he probably should be holding on to (to keep his position).inv
- I’m just being a dick. Good on himGnash
- Stripe is no small operation; we use it on 100% of our sites. @Jack is great and relatively elusive. Good on him.ideaist
- He could go a bit further with his efforts and shut down Trump's misinformation channel.Continuity
- ^The orange shithead is vengeful and will wreck twitter for all of us. Why should twitter suffer because of an American mistake?!grafician
- Weeeeeell, let's admit right now that Twitter isn't exactly an enlightened gift to the civilised world anyway, irrespective of his presence on it.Continuity
- Who will receive that money and what are they going to do with it?Bennn
- how much trumpcure do u get for that?... 2.50 is the bottle..mehehe.neverscared
- https://docs.google.…ideaist
- He’s donating more than BezosNBQ00
- https://twitter.com/…SlashPeckham
- Bill Gates has grown exponentially richer over the last 10 years? Why, then he must be worth upwards of Umpteen Quadrillion Space Dollars. The bastard!Nairn
- this guy stepped up in big way!utopian
- It's DAF, Donor-Advised Fund. Popular silicon valley accounting tactic for huge tax credit & avoid capital gains. In fact, it's legal not to spend a dime of itBustySaintClaire
- webazoot1
So on my Facebook its gone from Boris being seen as callous and dangerous with his herd imunity plan, his late call in closing schools and on both stages of the lockdown to just how well he's handled things, doing everything the country has asked of him, what a great leader... #clapforboris
A week is a long time in politics indeed.
- one of the even dwarves has got his back
https://twitter.com/…Bluejam - 'seven'Bluejam
- humanz flock to leaders in times of crisis.inteliboy
- one of the even dwarves has got his back
- webazoot3
I know this is about numbers but still...
A scientist who adapted his veterinary lab to test for disease among humans rather than salmon is being celebrated for helping the Faroe Islands avoid coronavirus deaths, where a larger proportion of the population has been tested than anywhere in the world.
https://www.theguardian.com/worl…
Meanwhile...
The health secretary, Matt Hancock, will ask industry leaders to help the UK find an antibody test that works.
Hancock will issue the plea on a conference call on Wednesday, echoing his call for help on ventilators, after the government conceded that none of the antibody tests it has are good enough for mass usage.
