pig flu outbreak

Out of context: Reply #356

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  • GeorgesII0

    ahahahahhaah thanks doc
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    Q: Is it surprising how quickly H1N1 adapted?

    Y.G.: All viruses, after interspecies transmission, will evolve fast. But why this H1N1 could become successful at efficient human-to-human transmission is still unknown. We have a knowledge gap about how influenza A viruses build up their pandemicity in humans. As swine H1N1 has being circulating in pigs since 1918, it has accumulated [many] differences from human H1N1 virus. So, for human beings, it looks like a novel subtype, as most human individuals lack immunity to this swine-like H1N1. This is one of the most important conditions for pandemic emergence. Whether the novel virus will develop into a more virulent strain—just like the Spanish flu did in the fall of 1918 to kill more people—we still don't have any idea.

    Q: It depends on further mutations?

    Y.G.: It depends on mutations and whether the virus further reassorts with other viruses—like H5N1. That could be a super nightmare for the whole world.

    Q: You’re talking about the Armageddon virus?

    Y.G.: The chance is very, very low that these two viruses will mix together, but we cannot rule out the possibility. Now, H5N1 is in more than 60 countries. It’s a panzootic, present everywhere except North America.

    Q: If the nightmare comes true?

    Y.G.: If that happens, I will retire immediately and lock myself in the P3 lab. H5N1 kills half the people it infects. Even if you inject yourself with a vaccine, it may be too late. Maybe in just a couple hours it takes your life.

    http://blogs.sciencemag.org/scie…

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